Accumulation and washout of 99mTc-sestamibi in osteoarthritic subchondral bone may indicate increased osteoclastic activity accompanying microfractures: a case study
نویسندگان
چکیده
منابع مشابه
Accumulation and washout of 99mTc-sestamibi in osteoarthritic subchondral bone may indicate increased osteoclastic activity accompanying microfractures: a case study.
We show for the first time that imaging of osteoarthritic subchondral bone with 99mTc-sestamibi (MIBI) may be a valuable diagnostic tool to assess the severity of subchondral sclerosis. This is a report on a patient who had osteoarthritis of both knees and where MIBI was accumulated in the lesion sites. Due to the accumulation of MIBI in the bone, we believe that excessive stress had been appli...
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INTRODUCTION Subchondral bone alterations represent an essential component of osteoarthritis (OA). Modifying the abnormal subchondral bone metabolism may be indicated to treat OA. We investigated the effect of diacerein and rhein on the changes occurring in subchondral bone during OA. To this end, we determined the drugs' effects on metalloprotease-13 (MMP-13) synthesis on subchondral bone and ...
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15 صفحه اولMeniscal extrusion predicts increases in subchondral bone marrow lesions and bone cysts and expansion of subchondral bone in osteoarthritic knees.
OBJECTIVES Meniscal extrusion is often present in knees with OA, and has been associated with cartilage changes. It is unknown whether meniscal extrusion is related to subchondral bone. The aim of the study was to examine the relationship between meniscal extrusion and knee cartilage and subchondral bone, and also changes in these structures over 2 years in a cohort with mild to moderate knee O...
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ژورنال
عنوان ژورنال: The Journal of Medical Investigation
سال: 2016
ISSN: 1343-1420,1349-6867
DOI: 10.2152/jmi.63.127